Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

PURPOSE: Hypermethylation of promoter CpG islands (CIMP) has been strongly implicated in chemotherapy resistance and is implicated in the pathogenesis of a subset of colorectal cancers (CRCs) termed CIMP-high. EXPERIMENTAL DESIGN: This phase I/II study in CRC (phase II portion restricted to CIMP-hig...

Szczegółowa specyfikacja

Zapisane w:
Opis bibliograficzny
Wydane w:Oncotarget
Główni autorzy: Overman, Michael J., Morris, Van, Moinova, Helen, Manyam, Ganiraju, Ensor, Joe, Lee, Michael S., Eng, Cathy, Kee, Bryan, Fogelman, David, Shroff, Rachna T., LaFramboise, Thomas, Mazard, Thibault, Feng, Tian, Hamilton, Stanley, Broom, Bradley, Lutterbaugh, James, Issa, Jean-Pierre, Markowitz, Sanford D., Kopetz, Scott
Format: Artigo
Język:Inglês
Wydane: Impact Journals LLC 2016
Hasła przedmiotowe:
Clinical Research Paper
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341892/
https://ncbi.nlm.nih.gov/pubmed/27542211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11317
Etykiety: Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!

Podobne zapisy