Identifying DNA Methylation Biomarkers for Non-Endoscopic Detection of Barrett’s Esophagus

We report a biomarker-based non-endoscopic method for detecting Barrett’s esophagus (BE), based on detecting methylated DNAs retrieved via a swallowable balloon-based esophageal sampling device. BE is the precursor of, and a major recognized risk factor for, developing esophageal adenocarcinoma (EAC...

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Publicat a:Sci Transl Med
Autors principals: Moinova, Helen R., LaFramboise, Thomas, Lutterbaugh, James D., Chandar, Apoorva Krishna, Dumot, John, Faulx, Ashley, Brock, Wendy, De la Cruz Cabrera, Omar, Guda, Kishore, Barnholtz-Sloan, Jill S., Iyer, Prasad G., Canto, Marcia I., Wang, Jean S., Shaheen, Nicholas J., Thota, Prashanti N., Willis, Joseph E., Chak, Amitabh, Markowitz, Sanford D.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789768/
https://ncbi.nlm.nih.gov/pubmed/29343623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aao5848
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