Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett’s Esophagus

BACKGROUND & AIMS: Aneuploidy has been proposed as a tool to assess progression in patients with Barrett’s Esophagus (BE), but has heretofore required multiple biopsies. We assessed whether a single esophageal brushing that widely sampled the esophagus could be combined with massively parallel s...

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Опубликовано в: :Gastroenterology
Главные авторы: Douville, Christopher, Moinova, Helen R., Thota, Prashanthi N., Shaheen, Nicholas J., Iyer, Prasad G., Canto, Marcia Irene, Wang, Jean S., Dumot, John, Faulx, Ashley, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Markowitz, Sanford D., Bettegowda, Chetan, Willis, Joseph E., Chak, Amitabh
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141353/
https://ncbi.nlm.nih.gov/pubmed/33493502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.01.209
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