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Massively Parallel Sequencing of Esophageal Brushings Enables an Aneuploidy-Based Classification of Patients with Barrett’s Esophagus

BACKGROUND & AIMS: Aneuploidy has been proposed as a tool to assess progression in patients with Barrett’s Esophagus (BE), but has heretofore required multiple biopsies. We assessed whether a single esophageal brushing that widely sampled the esophagus could be combined with massively parallel s...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Douville, Christopher, Moinova, Helen R., Thota, Prashanthi N., Shaheen, Nicholas J., Iyer, Prasad G., Canto, Marcia Irene, Wang, Jean S., Dumot, John, Faulx, Ashley, Kinzler, Kenneth W., Papadopoulos, Nickolas, Vogelstein, Bert, Markowitz, Sanford D., Bettegowda, Chetan, Willis, Joseph E., Chak, Amitabh
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8141353/
https://ncbi.nlm.nih.gov/pubmed/33493502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2021.01.209
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