Large-scale Domain Dynamics and Adenosylcobalamin Reorientation Orchestrate Radical Catalysis in Ornithine 4,5-Aminomutase

Por Wolthers, Kirsten R., Levy, Colin, Scrutton, Nigel S., Leys, David
Publicado em 2010

A Twin-track Approach Has Optimized Proton and Hydride Transfer by Dynamically Coupled Tunneling during the Evolution of Protochlorophyllide Oxidoreductase

Por Heyes, Derren J., Levy, Colin, Sakuma, Michiyo, Robertson, David L., Scrutton, Nigel S.
Publicado em 2011

An Internal Reaction Chamber in Dimethylglycine Oxidase Provides Efficient Protection from Exposure to Toxic Formaldehyde

Por Tralau, Tewes, Lafite, Pierre, Levy, Colin, Combe, John P., Scrutton, Nigel S., Leys, David
Publicado em 2009

The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer

Por Tunnicliffe, Richard B., Schacht, Mitchell, Levy, Colin, Jowitt, Thomas A., Sandri-Goldin, Rozanne M., Golovanov, Alexander P.
Publicado no Sci Rep (2015)

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

Por Gahloth, Deepankar, Levy, Colin, Walker, Louise, Wunderley, Lydia, Mould, A. Paul, Taylor, Sandra, Woodman, Philip, Tabernero, Lydia
Publicado no Structure (2017)

Structural basis of kynurenine 3-monooxygenase inhibition

Por Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.
Publicado em 2013

Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase

Por Khara, Basile, Menon, Navya, Levy, Colin, Mansell, David, Das, Debasis, Marsh, E Neil G, Leys, David, Scrutton, Nigel S
Publicado em 2013

Better than Nature: Nicotinamide Biomimetics That Outperform Natural Coenzymes

Por Knaus, Tanja, Paul, Caroline E., Levy, Colin W., de Vries, Simon, Mutti, Francesco G., Hollmann, Frank, Scrutton, Nigel S.
Publicado no J Am Chem Soc (2016)

A Structure‐Guided Switch in the Regioselectivity of a Tryptophan Halogenase

Por Shepherd, Sarah A., Menon, Binuraj R. K., Fisk, Heidi, Struck, Anna‐Winona, Levy, Colin, Leys, David, Micklefield, Jason
Publicado no Chembiochem (2016)

Effects of Active‐Site Modification and Quaternary Structure on the Regioselectivity of Catechol‐O‐Methyltransferase

Por Law, Brian J. C., Bennett, Matthew R., Thompson, Mark L., Levy, Colin, Shepherd, Sarah A., Leys, David, Micklefield, Jason
Publicado no Angew Chem Int Ed Engl (2016)

Biocatalytic Asymmetric Alkene Reduction: Crystal Structure and Characterization of a Double Bond Reductase from Nicotiana tabacum

Por Mansell, David J., Toogood, Helen S., Waller, John, Hughes, John M. X., Levy, Colin W., Gardiner, John M., Scrutton, Nigel S.
Publicado no ACS Catal (2013)

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

Por Levy, Colin, Pike, Katharine, Heyes, Derren J, Joyce, M Gordon, Gabor, Krisztina, Smidt, Hauke, van der Oost, John, Leys, David
Publicado em 2008

Carboplatin binding to histidine

Por Tanley, Simon W. M., Diederichs, Kay, Kroon-Batenburg, Loes M. J., Levy, Colin, Schreurs, Antoine M. M., Helliwell, John R.
Publicado em 2014

The Structure of Mycobacterium tuberculosis CYP125: MOLECULAR BASIS FOR CHOLESTEROL BINDING IN A P450 NEEDED FOR HOST INFECTION

Por McLean, Kirsty J., Lafite, Pierre, Levy, Colin, Cheesman, Myles R., Mast, Natalia, Pikuleva, Irina A., Leys, David, Munro, Andrew W.
Publicado em 2009

Purification, crystallization and preliminary crystallographic analysis of Arabidopsis thaliana imidazoleglycerol-phosphate dehydratase

Por Glynn, Steven E., Baker, Patrick J., Sedelnikova, Svetlana E., Levy, Colin W., Rodgers, H. Fiona, Blank, Jutta, Hawkes, Timothy R., Rice, David W.
Publicado em 2005

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

Por Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Publicado no Biochemistry (2015)

Updated structure of Drosophila cryptochrome

Por Levy, Colin, Zoltowski, Brian D., Jones, Alex R., Vaidya, Anand T., Top, Deniz, Widom, Joanne, Young, Michael W., Scrutton, Nigel S., Crane, Brian R., Leys, David
Publicado em 2013

Reductive dehalogenase structure suggests a mechanism for B12-dependent dehalogenation

Por Payne, Karl AP, Quezada, Carolina P, Fisher, Karl, Dunstan, Mark S, Collins, Fraser A, Sjuts, Hanno, Levy, Colin, Hay, Sam, Rigby, Stephen EJ, Leys, David
Publicado no Nature (2014)

Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1

Por Gahloth, Deepankar, Levy, Colin, Heaven, Graham, Stefani, Flavia, Wunderley, Lydia, Mould, Paul, Cliff, Matthew J., Bella, Jordi, Fielding, Alistair J., Woodman, Philip, Tabernero, Lydia
Publicado no Structure (2016)

Structural and Biochemical Characterization of Mycobacterium tuberculosis CYP142: EVIDENCE FOR MULTIPLE CHOLESTEROL 27-HYDROXYLASE ACTIVITIES IN A HUMAN PATHOGEN

Por Driscoll, Max D., McLean, Kirsty J., Levy, Colin, Mast, Natalia, Pikuleva, Irina A., Lafite, Pierre, Rigby, Stephen E. J., Leys, David, Munro, Andrew W.
Publicado em 2010