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Carboplatin binding to histidine

Carboplatin is a second-generation platinum anticancer agent used for the treatment of a variety of cancers. Previous X-ray crystallographic studies of carboplatin binding to histidine (in hen egg-white lysozyme; HEWL) showed the partial conversion of carboplatin to cisplatin owing to the high NaCl...

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Detalhes bibliográficos
Main Authors: Tanley, Simon W. M., Diederichs, Kay, Kroon-Batenburg, Loes M. J., Levy, Colin, Schreurs, Antoine M. M., Helliwell, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157408/
https://ncbi.nlm.nih.gov/pubmed/25195881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14016161
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