Spectroscopic and kinetic characterization of the light-dependent enzyme protochlorophyllide oxidoreductase (POR) using monovinyl and divinyl substrates

Por Heyes, Derren J., Kruk, Jerzy, Hunter, C. Neil
Publicado em 2006

Does the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H‐transfer reactions?

Por Hoeven, Robin, Heyes, Derren J., Hay, Sam, Scrutton, Nigel S.
Publicado no FEBS J (2015)

Enzymology below 200 K: The kinetics and thermodynamics of the photochemistry catalyzed by protochlorophyllide oxidoreductase

Por Heyes, Derren J., Ruban, Alexander V., Wilks, Helen M., Hunter, C. Neil
Publicado em 2002

Cryogenic and Laser Photoexcitation Studies Identify Multiple Roles for Active Site Residues in the Light-driven Enzyme Protochlorophyllide Oxidoreductase

Por Menon, Binuraj R. K., Waltho, Jonathan P., Scrutton, Nigel S., Heyes, Derren J.
Publicado em 2009

A Twin-track Approach Has Optimized Proton and Hydride Transfer by Dynamically Coupled Tunneling during the Evolution of Protochlorophyllide Oxidoreductase

Por Heyes, Derren J., Levy, Colin, Sakuma, Michiyo, Robertson, David L., Scrutton, Nigel S.
Publicado em 2011

Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR)()

Por Menon, Binuraj R.K., Hardman, Samantha J.O., Scrutton, Nigel S., Heyes, Derren J.
Publicado no J Photochem Photobiol B (2016)

Mechanistic Reappraisal of Early Stage Photochemistry in the Light-Driven Enzyme Protochlorophyllide Oxidoreductase

Por Heyes, Derren J., Hardman, Samantha J. O., Mansell, David, Gardiner, John M., Scrutton, Nigel S.
Publicado em 2012

Mutagenesis Alters the Catalytic Mechanism of the Light-driven Enzyme Protochlorophyllide Oxidoreductase

Por Menon, Binuraj R. K., Davison, Paul A., Hunter, C. Neil, Scrutton, Nigel S., Heyes, Derren J.
Publicado em 2010

Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers

Por Peers, Martyn K., Toogood, Helen S., Heyes, Derren J., Mansell, David, Coe, Benjamin J., Scrutton, Nigel S.
Publicado no Catal Sci Technol (2016)

Comprehensive Analysis of the Green-to-Blue Photoconversion of Full-Length Cyanobacteriochrome Tlr0924

Por Hardman, Samantha J.O., Hauck, Anna F.E., Clark, Ian P., Heyes, Derren J., Scrutton, Nigel S.
Publicado no Biophys J (2014)

Demonstration of Proton-coupled Electron Transfer in the Copper-containing Nitrite Reductases

Por Brenner, Sibylle, Heyes, Derren J., Hay, Sam, Hough, Michael A., Eady, Robert R., Hasnain, S. Samar, Scrutton, Nigel S.
Publicado em 2009

Structural basis of kynurenine 3-monooxygenase inhibition

Por Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.
Publicado em 2013

The Photoinitiated Reaction Pathway of Full-length Cyanobacteriochrome Tlr0924 Monitored Over 12 Orders of Magnitude

Por Hauck, Anna F. E., Hardman, Samantha J. O., Kutta, Roger J., Greetham, Gregory M., Heyes, Derren J., Scrutton, Nigel S.
Publicado em 2014

Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase**

Por Heyes, Derren J, Hardman, Samantha J O, Hedison, Tobias M, Hoeven, Robin, Greetham, Greg M, Towrie, Michael, Scrutton, Nigel S
Publicado no Angew Chem Int Ed Engl (2015)

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

Por Levy, Colin, Pike, Katharine, Heyes, Derren J, Joyce, M Gordon, Gabor, Krisztina, Smidt, Hauke, van der Oost, John, Leys, David
Publicado em 2008

Simultaneous Measurements of Solvent Dynamics and Functional Kinetics in a Light-Activated Enzyme

Por Durin, Guillaume, Delaunay, Aude, Darnault, Claudine, Heyes, Derren J., Royant, Antoine, Vernede, Xavier, Hunter, C. Neil, Weik, Martin, Bourgeois, Dominique
Publicado em 2009

Ultrafast Red Light Activation of Synechocystis Phytochrome Cph1 Triggers Major Structural Change to Form the Pfr Signalling-Competent State

Por Heyes, Derren J., Khara, Basile, Sakuma, Michiyo, Hardman, Samantha J. O., O'Cualain, Ronan, Rigby, Stephen E. J., Scrutton, Nigel S.
Publicado em 2012

Energy Landscapes and Catalysis in Nitric-oxide Synthase

Por Sobolewska-Stawiarz, Anna, Leferink, Nicole G. H., Fisher, Karl, Heyes, Derren J., Hay, Sam, Rigby, Stephen E. J., Scrutton, Nigel S.
Publicado em 2014

Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range

Por Russell, Henry J., Hardman, Samantha J. O., Heyes, Derren J., Hough, Michael A., Greetham, Gregory M., Towrie, Michael, Hay, Sam, Scrutton, Nigel S.
Publicado em 2013

Origin of the Proton-transfer Step in the Cofactor-free (1H)-3-Hydroxy-4-oxoquinaldine 2,4-Dioxygenase: EFFECT OF THE BASICITY OF AN ACTIVE SITE HIS RESIDUE

Por Hernandez-Ortega, Aitor, Quesne, Matthew G., Bui, Soi, Heuts, Dominic P. H. M., Steiner, Roberto A., Heyes, Derren J., de Visser, Sam P., Scrutton, Nigel S.
Publicado em 2014