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Modulation of ligand–heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond–second temporal range

The ability of hemoproteins to discriminate between diatomic molecules, and the subsequent affinity for their chosen ligand, is fundamental to the existence of life. These processes are often controlled by precise structural arrangements in proteins, with heme pocket residues driving reactivity and...

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Detalhes bibliográficos
Main Authors: Russell, Henry J., Hardman, Samantha J. O., Heyes, Derren J., Hough, Michael A., Greetham, Gregory M., Towrie, Michael, Hay, Sam, Scrutton, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163637/
https://ncbi.nlm.nih.gov/pubmed/24034856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.12526
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