The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton...

Autor Johannissen, Linus O., Scrutton, Nigel S., Sutcliffe, Michael J.
Vydáno 2008

Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

Autor Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
Vydáno 2010

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

Autor Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
Vydáno 2011

Vertebrate Cryptochromes are Vestigial Flavoproteins

Autor Kutta, Roger J., Archipowa, Nataliya, Johannissen, Linus O., Jones, Alex R., Scrutton, Nigel S.
Vydáno v Sci Rep (2017)

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

Autor Issa, Issa S., Toogood, Helen S., Johannissen, Linus O., Raftery, James, Scrutton, Nigel S., Gardiner, John M.
Vydáno v Chemistry (2019)

Identification of B cell epitopes enhanced by protein unfolding and aggregation

Autor Eyes, Timothy J., Austerberry, James I., Dearman, Rebecca J., Johannissen, Linus O., Kimber, Ian, Smith, Noel, Thistlethwaite, Angela, Derrick, Jeremy P.
Vydáno v Mol Immunol (2019)

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

Autor Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Vydáno v J Biol Chem (2020)

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

Autor Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Vydáno v Biochemistry (2015)

Hydrogen tunnelling in enzyme-catalysed H-transfer reactions: flavoprotein and quinoprotein systems

Autor Sutcliffe, Michael J, Masgrau, Laura, Roujeinikova, Anna, Johannissen, Linus O, Hothi, Parvinder, Basran, Jaswir, Ranaghan, Kara E, Mulholland, Adrian J, Leys, David, Scrutton, Nigel S
Vydáno 2006

Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor

Autor Camacho, Inês S., Theisen, Alina, Johannissen, Linus O., Díaz-Ramos, L. Aranzazú, Christie, John M., Jenkins, Gareth I., Bellina, Bruno, Barran, Perdita, Jones, Alex R.
Vydáno v Proc Natl Acad Sci U S A (2019)

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

Autor Leferink, Nicole G. H., Ranaghan, Kara E., Battye, Jaime, Johannissen, Linus O., Hay, Sam, van der Kamp, Marc W., Mulholland, Adrian J., Scrutton, Nigel S.
Vydáno v Chembiochem (2019)

Interplay between chromophore binding and domain assembly by the B(12)-dependent photoreceptor protein, CarH

Autor Camacho, Inês S., Black, Rachelle, Heyes, Derren J., Johannissen, Linus O., Ramakers, Lennart A. I., Bellina, Bruno, Barran, Perdita E., Hay, Sam, Jones, Alex R.
Vydáno v Chem Sci (2021)

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

Autor Czarnota, Sylwia, Johannissen, Linus O., Baxter, Nicola J., Rummel, Felix, Wilson, Alex L., Cliff, Matthew J., Levy, Colin W., Scrutton, Nigel S., Waltho, Jonathan P., Hay, Sam
Vydáno v ACS Catal (2019)

The photochemical mechanism of a B(12)-dependent photoreceptor protein

Autor Kutta, Roger J., Hardman, Samantha J. O., Johannissen, Linus O., Bellina, Bruno, Messiha, Hanan L., Ortiz-Guerrero, Juan Manuel, Elías-Arnanz, Montserrat, Padmanabhan, S., Barran, Perdita, Scrutton, Nigel S., Jones, Alex R.
Vydáno v Nat Commun (2015)

Engineering the “Missing Link” in Biosynthetic (−)-Menthol Production: Bacterial Isopulegone Isomerase

Autor Currin, Andrew, Dunstan, Mark S., Johannissen, Linus O., Hollywood, Katherine A., Vinaixa, Maria, Jervis, Adrian J., Swainston, Neil, Rattray, Nicholas J. W., Gardiner, John M., Kell, Douglas B., Takano, Eriko, Toogood, Helen S., Scrutton, Nigel S.
Vydáno v ACS Catal (2018)

Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase

Autor Karuppiah, Vijaykumar, Ranaghan, Kara E., Leferink, Nicole G. H., Johannissen, Linus O., Shanmugam, Muralidharan, Ní Cheallaigh, Aisling, Bennett, Nathan J., Kearsey, Lewis J., Takano, Eriko, Gardiner, John M., van der Kamp, Marc W., Hay, Sam, Mulholland, Adrian J., Leys, David, Scrutton, Nigel S.
Vydáno v ACS Catal (2017)