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Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

It is generally accepted that enzymes catalyze reactions by lowering the apparent activation energy by transition state stabilization or through destabilization of ground states. A more controversial proposal is that enzymes can also accelerate reactions through barrier compression—an idea that has...

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Detalhes bibliográficos
Main Authors: Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800970/
https://ncbi.nlm.nih.gov/pubmed/20085724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.045
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