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Barrier Compression and Its Contribution to Both Classical and Quantum Mechanical Aspects of Enzyme Catalysis

It is generally accepted that enzymes catalyze reactions by lowering the apparent activation energy by transition state stabilization or through destabilization of ground states. A more controversial proposal is that enzymes can also accelerate reactions through barrier compression—an idea that has...

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Autors principals: Hay, Sam, Johannissen, Linus O., Sutcliffe, Michael J., Scrutton, Nigel S.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2800970/
https://ncbi.nlm.nih.gov/pubmed/20085724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.09.045
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