Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

[Image: see text] The Fe(II)- and 2-oxoglutarate (2-OG)-dependent dioxygenases comprise a large and diverse enzyme superfamily the members of which have multiple physiological roles. Despite this diversity, these enzymes share a common chemical mechanism and a core structural fold, a double-stranded...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4613865/
https://ncbi.nlm.nih.gov/pubmed/26368022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00789
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