Dissecting the role of His domain protein tyrosine phosphatase/PTPN23 and ESCRTs in sorting activated epidermal growth factor receptor to the multivesicular body

por Tabernero, Lydia, Woodman, Philip
Publicado no Biochem Soc Trans (2018)

Computational and structure-guided design of phosphoinositide substrate specificity into the tyrosine specific LMW-PTP enzyme

por Egbe, Eyong, Levy, Colin W., Tabernero, Lydia
Publicado no PLoS One (2020)

Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis

por Buiga, Petronela, Elson, Ari, Tabernero, Lydia, Schwartz, Jean-Marc
Publicado no BMC Syst Biol (2018)

Kinetic Modeling of DUSP Regulation in Herceptin-Resistant HER2-Positive Breast Cancer

por Buiga, Petronela, Elson, Ari, Tabernero, Lydia, Schwartz, Jean-Marc
Publicado no Genes (Basel) (2019)

Class II 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductases

por Hedl, Matija, Tabernero, Lydia, Stauffacher, Cynthia V., Rodwell, Victor W.
Publicado em 2004

The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex

por Wunderley, Lydia, Brownhill, Kim, Stefani, Flavia, Tabernero, Lydia, Woodman, Philip
Publicado em 2014

Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl–CoA reductase

por Tabernero, Lydia, Bochar, Daniel A., Rodwell, Victor W., Stauffacher, Cynthia V.
Publicado em 1999

Molecular Mechanisms of Primary Resistance to Flucytosine in Candida albicans

por Hope, William W., Tabernero, Lydia, Denning, David W., Anderson, Michael J.
Publicado em 2004

Membrane-impermeable Cross-linking Provides Evidence for Homophilic, Isoform-specific Binding of Desmosomal Cadherins in Epithelial Cells

por Nie, Zhuxiang, Merritt, Anita, Rouhi-Parkouhi, Mansour, Tabernero, Lydia, Garrod, David
Publicado em 2011

VSpipe, an Integrated Resource for Virtual Screening and Hit Selection: Applications to Protein Tyrosine Phospahatase Inhibition

por Álvarez-Carretero, Sandra, Pavlopoulou, Niki, Adams, James, Gilsenan, Jane, Tabernero, Lydia
Publicado no Molecules (2018)

Protein tyrosine phosphatase TbPTP1: a molecular switch controlling life cycle differentiation in trypanosomes

por Szöőr, Balázs, Wilson, Jude, McElhinney, Helen, Tabernero, Lydia, Matthews, Keith R.
Publicado em 2006

A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis

por Beresford, Nicola J, Saville, Charis, Bennett, Hayley J, Roberts, Ian S, Tabernero, Lydia
Publicado em 2010

MptpB, a virulence factor from Mycobacterium tuberculosis, exhibits triple-specificity phosphatase activity

por Beresford, Nicola, Patel, Sumayya, Armstrong, Jane, Szöor, Balázs, Fordham-Skelton, Anthony P., Tabernero, Lydia
Publicado em 2007

Characteristics of the First Protein Tyrosine Phosphatase with Phytase Activity from a Soil Metagenome

por Castillo Villamizar, Genis Andrés, Nacke, Heiko, Griese, Laura, Tabernero, Lydia, Funkner, Katrina, Daniel, Rolf
Publicado no Genes (Basel) (2019)

Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs

por Fernandez-Soto, Paulina, Bruce, Alexander J. E., Fielding, Alistair J., Cavet, Jennifer S., Tabernero, Lydia
Publicado no Sci Rep (2019)

Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

por Gahloth, Deepankar, Levy, Colin, Walker, Louise, Wunderley, Lydia, Mould, A. Paul, Taylor, Sandra, Woodman, Philip, Tabernero, Lydia
Publicado no Structure (2017)

The TriTryp Phosphatome: analysis of the protein phosphatase catalytic domains

por Brenchley, Rachel, Tariq, Humera, McElhinney, Helen, Szöőr, Balázs, Huxley-Jones, Julie, Stevens, Robert, Matthews, Keith, Tabernero, Lydia
Publicado em 2007

The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function

por Gahloth, Deepankar, Heaven, Graham, Jowitt, Thomas A., Mould, A. Paul, Bella, Jordi, Baldock, Clair, Woodman, Philip, Tabernero, Lydia
Publicado no Sci Rep (2017)

Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening

por Thornton, Benjamin P., Johns, Anna, Al-Shidhani, Reem, Álvarez-Carretero, Sandra, Storer, Isabelle S. R., Bromley, Michael J., Tabernero, Lydia
Publicado no Int J Mol Sci (2019)

Cadherin flexibility provides a key difference between desmosomes and adherens junctions

por Tariq, Humera, Bella, Jordi, Jowitt, Thomas A., Holmes, David F., Rouhi, Mansour, Nie, Zhuxiang, Baldock, Clair, Garrod, David, Tabernero, Lydia
Publicado no Proc Natl Acad Sci U S A (2015)