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The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function

HD-PTP is a tumour suppressor phosphatase that controls endocytosis, down-regulation of mitogenic receptors and cell migration. Central to its role is the specific recruitment of critical endosomal sorting complexes required for transport (ESCRTs). However, the molecular mechanisms that enable HD-PT...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Gahloth, Deepankar, Heaven, Graham, Jowitt, Thomas A., Mould, A. Paul, Bella, Jordi, Baldock, Clair, Woodman, Philip, Tabernero, Lydia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567221/
https://ncbi.nlm.nih.gov/pubmed/28831121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09467-9
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