Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

SARA and endofin are endosomal adaptor proteins that drive Smad phosphorylation by ligand-activated transforming growth factor β/bone morphogenetic protein (TGFβ/BMP) receptors. We show in this study that SARA and endofin also recruit the tumor supressor HD-PTP, a master regulator of endosomal sorti...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Structure
Auteurs principaux: Gahloth, Deepankar, Levy, Colin, Walker, Louise, Wunderley, Lydia, Mould, A. Paul, Taylor, Sandra, Woodman, Philip, Tabernero, Lydia
Format: Artigo
Langue:Inglês
Publié: Cell Press 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501724/
https://ncbi.nlm.nih.gov/pubmed/28602823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.005
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires