Structural Basis for Specific Interaction of TGFβ Signaling Regulators SARA/Endofin with HD-PTP

SARA and endofin are endosomal adaptor proteins that drive Smad phosphorylation by ligand-activated transforming growth factor β/bone morphogenetic protein (TGFβ/BMP) receptors. We show in this study that SARA and endofin also recruit the tumor supressor HD-PTP, a master regulator of endosomal sorti...

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Publicado en:Structure
Autores principales: Gahloth, Deepankar, Levy, Colin, Walker, Louise, Wunderley, Lydia, Mould, A. Paul, Taylor, Sandra, Woodman, Philip, Tabernero, Lydia
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501724/
https://ncbi.nlm.nih.gov/pubmed/28602823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2017.05.005
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