Molecular Mechanisms of Primary Resistance to Flucytosine in Candida albicans

Primary resistance in Candida albicans to flucytosine (5-FC) was investigated in 25 strains by identifying and sequencing the genes FCA1, FUR1, FCY21, and FCY22, which code for cytosine deaminase, uracil phosphoribosyltransferase (UPRT), and two purine-cytosine permeases, respectively. These protein...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Hope, William W., Tabernero, Lydia, Denning, David W., Anderson, Michael J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC525410/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15504867/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.11.4377-4386.2004
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