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Molecular Mechanisms of Primary Resistance to Flucytosine in Candida albicans

Primary resistance in Candida albicans to flucytosine (5-FC) was investigated in 25 strains by identifying and sequencing the genes FCA1, FUR1, FCY21, and FCY22, which code for cytosine deaminase, uracil phosphoribosyltransferase (UPRT), and two purine-cytosine permeases, respectively. These protein...

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Detalhes bibliográficos
Main Authors: Hope, William W., Tabernero, Lydia, Denning, David W., Anderson, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC525410/
https://ncbi.nlm.nih.gov/pubmed/15504867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.11.4377-4386.2004
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