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Clade-Specific Flucytosine Resistance Is Due to a Single Nucleotide Change in the FUR1 Gene of Candida albicans

Population studies have indicated that natural resistance to flucytosine (5FC) in Candida albicans is limited to one of the five major clades, clade I. In addition, while 73% of clade I isolates are less susceptible to 5FC (MIC ≥ 0.5 μg/ml), only 2% of non-clade I isolates are less susceptible. In o...

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Bibliografische gegevens
Hoofdauteurs: Dodgson, Andrew R., Dodgson, Kirsty J., Pujol, Claude, Pfaller, Michael A., Soll, David R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC415630/
https://ncbi.nlm.nih.gov/pubmed/15155225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2223-2227.2004
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