The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs

Por Langley, Robert R., Fidler, Isaiah J.
Publicado em 2011

Interleukin-6, Secreted by Human Ovarian Carcinoma Cells, Is a Potent Proangiogenic Cytokine

Por Nilsson, Monique B., Langley, Robert R., Fidler, Isaiah J.
Publicado em 2005

Modulation of the cancer cell transcriptome by culture media formulations and cell density

Por KIM, SEUNG WOOK, KIM, SUN-JIN, LANGLEY, ROBERT R., FIDLER, ISAIAH J.
Publicado no Int J Oncol (2015)

A Homeobox Gene Related to Drosophila Distal-Less Promotes Ovarian Tumorigenicity by Inducing Expression of Vascular Endothelial Growth Factor and Fibroblast Growth Factor-2

Por Hara, Fumikata, Samuel, Shaija, Liu, Jinsong, Rosen, Daniel, Langley, Robert R., Naora, Honami
Publicado em 2007

Targeting Receptor Tyrosine Kinase on Lymphatic Endothelial Cells for the Therapy of Colon Cancer Lymph Node Metastasis

Por Rebhun, Robert B, Langley, Robert R, Yokoi, Kenji, Fan, Dominic, Gershenwald, Jeffrey E, Fidler, Isaiah J
Publicado em 2006

Constitutive Expression of the α(4) Integrin Correlates with Tumorigenicity and Lymph Node Metastasis of the B16 Murine Melanoma

Por Rebhun, Robert B, Cheng, Hua, Gershenwald, Jeffrey E, Fan, Dominic, Fidler, Isaiah J, Langley, Robert R
Publicado em 2010

Construction of a Novel Constitutively Active Chimeric EGFR to Identify New Targets for Therapy

Por Cheng, Hua, Langley, Robert R, Wu, Qiuyu, Wu, Wenjuan, Feng, Jie, Tsan, Rachel, Fan, Dominic, Fidler, Isaiah J
Publicado em 2005

Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro

Por Ando, Tomoaki, Langley, Robert R, Wang, Yuping, Jordan, Paul A, Minagar, Alireza, Alexander, J Steven, Jennings, Merilyn H
Publicado em 2007

Selection of Brain Metastasis-Initiating Breast Cancer Cells Determined by Growth on Hard Agar

Por Guo, Lixia, Fan, Dominic, Zhang, Fahao, Price, Janet E., Lee, Ju-Seog, Marchetti, Dario, Fidler, Isaiah J., Langley, Robert R.
Publicado em 2011

Modification of the Primary Tumor Microenvironment by Transforming Growth Factor α-Epidermal Growth Factor Receptor Signaling Promotes Metastasis in an Orthotopic Colon Cancer Mode...

Por Sasaki, Takamitsu, Nakamura, Toru, Rebhun, Robert B., Cheng, Hua, Hale, Katherine Stemke, Tsan, Rachel Z., Fidler, Isaiah J., Langley, Robert R.
Publicado em 2008

Generation of an Immortalized Astrocyte Cell Line from H-2K(b)-tsA58 Mice to Study the Role of Astrocytes in Brain Metastasis

Por Langley, Robert R., Fan, Dominic, Guo, Lixia, Zhang, Chenyu, Lin, Qingtang, Brantley, Emily C., McCarty, Joseph H., Fidler, Isaiah J.
Publicado em 2009

Intratumoral Heterogeneity for Expression of Tyrosine Kinase Growth Factor Receptors in Human Colon Cancer Surgical Specimens and Orthotopic Tumors

Por Kuwai, Toshio, Nakamura, Toru, Kim, Sun-Jin, Sasaki, Takamitsu, Kitadai, Yasuhiko, Langley, Robert R., Fan, Dominic, Hamilton, Stanley R., Fidler, Isaiah J.
Publicado em 2008

Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells

Por Kim, Seung Wook, Choi, Hyun Jin, Lee, Ho-Jeong, He, Junqin, Wu, Qiuyu, Langley, Robert R., Fidler, Isaiah J., Kim, Sun-Jin
Publicado no Neuro Oncol (2014)

DNA Damage-induced Nuclear Export of Precursor MicroRNAs is Regulated by the ATM-AKT Pathway

Por Wan, Guohui, Zhang, Xinna, Langley, Robert R., Liu, Yunhua, Hu, Xiaoxiao, Han, Cecil, Peng, Guang, Ellis, Lee M., Jones, Stephen N., Lu, Xiongbin
Publicado em 2013

Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse

Por Giordano, Ricardo J., Lahdenranta, Johanna, Zhen, Lijie, Chukwueke, Ugonma, Petrache, Irina, Langley, Robert R., Fidler, Isaiah J., Pasqualini, Renata, Tuder, Rubin M., Arap, Wadih
Publicado em 2008

Inhibition of Epidermal Growth Factor Receptor and Vascular Endothelial Growth Factor Receptor Phosphorylation on Tumor-Associated Endothelial Cells Leads to Treatment of Orthotopi...

Por Sasaki, Takamitsu, Kitadai, Yasuhiko, Nakamura, Toru, Kim, Jang-Seong, Tsan, Rachel Z, Kuwai, Toshio, Langley, Robert R, Fan, Dominic, Kim, Sun-Jin, Fidler, Isaiah J
Publicado em 2007

Treatment of experimental human breast cancer and lung cancer brain metastases in mice by macitentan, a dual antagonist of endothelin receptors, combined with paclitaxel

Por Lee, Ho Jeong, Hanibuchi, Masaki, Kim, Sun-Jin, Yu, Hyunkyung, Kim, Mark Seungwook, He, Junqin, Langley, Robert R., Lehembre, François, Regenass, Urs, Fidler, Isaiah J.
Publicado no Neuro Oncol (2016)

Consistent interactions between tumor cell IL-6 and macrophage TNF-α enhance the growth of human prostate cancer cells in the bone of nude mouse

Por Kim, Seung Wook, Kim, Jang Seong, Papadopoulos, John, Choi, Hyun Jin, He, Junqin, Maya, Marva, Langley, Robert R., Fan, Dominic, Fidler, Isaiah J, Kim, Sun-Jin
Publicado em 2011

Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

Por Lahat, Guy, Zhu, Quan-Sheng, Huang, Kai-Lieh, Wang, Suizhao, Bolshakov, Svetlana, Liu, Jeffery, Torres, Keila, Langley, Robert R., Lazar, Alexander J., Hung, Mien Chie, Lev, Dina
Publicado em 2010

Role of the gp85/Trans-Sialidases in Trypanosoma cruzi Tissue Tropism: Preferential Binding of a Conserved Peptide Motif to the Vasculature In Vivo

Por Tonelli, Renata R., Giordano, Ricardo J., Barbu, Elena Magda, Torrecilhas, Ana Claudia, Kobayashi, Gerson S., Langley, Robert R., Arap, Wadih, Pasqualini, Renata, Colli, Walter, Alves, Maria Júlia M.
Publicado em 2010