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Inflammatory cytokines induce MAdCAM-1 in murine hepatic endothelial cells and mediate alpha-4 beta-7 integrin dependent lymphocyte endothelial adhesion In Vitro

BACKGROUND: MAdCAM-1 plays a central role in T-lymphocyte homing to the gut, but its role in chronic liver inflammation remains unknown. Therefore, this study measured MAdCAM-1 expression, regulation, and function in cultured murine hepatic endothelial cells. METHODS: Cultures of hepatic endothelial...

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Main Authors: Ando, Tomoaki, Langley, Robert R, Wang, Yuping, Jordan, Paul A, Minagar, Alireza, Alexander, J Steven, Jennings, Merilyn H
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045088/
https://ncbi.nlm.nih.gov/pubmed/17868448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-7-10
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