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TNF-α induced endothelial MAdCAM-1 expression is regulated by exogenous, not endogenous nitric oxide

BACKGROUND: MAdCAM-1 is an adhesion molecule expressed in Peyer's patches and lymphoid tissues which is mobilized by cytokines like TNF-α and is a major determinant of lymphocyte trafficking to the gut in human inflammatory bowel disease (IBD). It has been suggested that both reactive oxygen an...

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Detalhes bibliográficos
Main Authors: Oshima, Tadayuki, Jordan, Paul, Grisham, Matthew B, Alexander, Jonathan S, Jennings, Merilyn, Sasaki, Makotoh, Manas, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC35355/
https://ncbi.nlm.nih.gov/pubmed/11481030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-1-5
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