Transfection of IL-10 expression vectors into endothelial cultures attenuates α4β7-dependent lymphocyte adhesion mediated by MAdCAM-1

BACKGROUND: Enhanced expression of MAdCAM-1 (mucosal addressin cell adhesion molecule-1) is associated with the onset and progression of inflammatory bowel disease. The clinical significance of elevated MAdCAM-1 expression is supported by studies showing that immunoneutralization of MAdCAM-1, or its...

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Bibliografiska uppgifter
Huvudupphovsmän: Sasaki, Makoto, Jordan, Paul, Houghton, Jeff, Meng, Xianmin, Itoh, Makoto, Joh, Takashi, Alexander, J Steven
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2003
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC151603/
https://ncbi.nlm.nih.gov/pubmed/12625840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-3-3
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