Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Normal mouse lungs lack appreciable numbers of mast cells (MCs) or MC progenitors (MCp's), yet the appearance of mature MCs in the tracheobronchial epithelial surface is a characteristic of allergic, T-cell-dependent pulmonary inflammation. We hypothesized that pulmonary inflammation would recr...

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Main Authors: Abonia, J. Pablo, Hallgren, Jenny, Jones, Tatiana, Shi, Tong, Xu, Yuhui, Koni, Pandelakis, Flavell, Richard A., Boyce, Joshua A., Austen, K. Frank, Gurish, Michael F.
Format: Artigo
Jezik:Inglês
Izdano: © 2006 by The American Society of Hematology 2006
Teme:
Immunobiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895513/
https://ncbi.nlm.nih.gov/pubmed/16670268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-12-012781
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