Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Normal mouse lungs lack appreciable numbers of mast cells (MCs) or MC progenitors (MCp's), yet the appearance of mature MCs in the tracheobronchial epithelial surface is a characteristic of allergic, T-cell-dependent pulmonary inflammation. We hypothesized that pulmonary inflammation would recr...

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Hlavní autoři: Abonia, J. Pablo, Hallgren, Jenny, Jones, Tatiana, Shi, Tong, Xu, Yuhui, Koni, Pandelakis, Flavell, Richard A., Boyce, Joshua A., Austen, K. Frank, Gurish, Michael F.
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
Immunobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895513/
https://ncbi.nlm.nih.gov/pubmed/16670268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-12-012781
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