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MAdCAM costimulation through Integrin-α(4)β(7) promotes HIV replication

Human gut associated lymphoid tissues (GALT) play a key role in the acute phase of HIV infection. The propensity of HIV to replicate in these tissues however, is not fully understood. Access and migration of naïve and memory CD4(+) T cells to these sites is mediated by interactions between integrin...

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Bibliographic Details
Published in:Mucosal Immunol
Main Authors: Nawaz, Fatima, Goes, Livia R., Ray, Jocelyn C., Olowojesiku, Ronke, Sajani, Alia, Ansari, Aftab A., Perrone, Ian, Hiatt, Joseph, Van Ryk, Donald, Wei, Danlan, Waliszewski, Mia, Soares, Marcelo A., Jelicic, Katija, Connors, Mark, Migueles, Stephen A., Martinelli, Elena, Villinger, Francois, Cicala, Claudia, Fauci, Anthony S., Arthos, James
Format: Artigo
Language:Inglês
Published: 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160318/
https://ncbi.nlm.nih.gov/pubmed/29875402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0044-1
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