Signal peptide of HIV envelope protein impacts glycosylation and antigenicity of gp120

The HIV-1 envelope protein (Env) of early-replicating viruses encodes several distinct transmission signatures. One such signature involves a reduced number of potential N-linked glycosylation sites (PNGs). This transmission signature underscores the importance of posttranslational modifications in...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Yolitz, Jason, Schwing, Catherine, Chang, Julia, Van Ryk, Donald, Nawaz, Fatima, Wei, Danlan, Cicala, Claudia, Arthos, James, Fauci, Anthony S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877976/
https://ncbi.nlm.nih.gov/pubmed/29463753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1722627115
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