Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung

Normal mouse lungs lack appreciable numbers of mast cells (MCs) or MC progenitors (MCp's), yet the appearance of mature MCs in the tracheobronchial epithelial surface is a characteristic of allergic, T-cell-dependent pulmonary inflammation. We hypothesized that pulmonary inflammation would recr...

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Bibliographic Details
Main Authors: Abonia, J. Pablo, Hallgren, Jenny, Jones, Tatiana, Shi, Tong, Xu, Yuhui, Koni, Pandelakis, Flavell, Richard A., Boyce, Joshua A., Austen, K. Frank, Gurish, Michael F.
Format: Artigo
Language:Inglês
Published: © 2006 by The American Society of Hematology 2006
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895513/
https://ncbi.nlm.nih.gov/pubmed/16670268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-12-012781
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