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Constitutive Expression of the α(4) Integrin Correlates with Tumorigenicity and Lymph Node Metastasis of the B16 Murine Melanoma

The lymphatic system plays a critical role in melanoma metastasis, and yet, virtually no information exists regarding the cellular and molecular mechanisms that take place between melanoma cells and the lymphatic vasculature. Here, we generated B16-F1 melanoma cells that expressed high (B16α(4)+) an...

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Detalhes bibliográficos
Main Authors: Rebhun, Robert B, Cheng, Hua, Gershenwald, Jeffrey E, Fan, Dominic, Fidler, Isaiah J, Langley, Robert R
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814355/
https://ncbi.nlm.nih.gov/pubmed/20126475
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