Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft Studies

BACKGROUND: Vimentin is a ubiquitous mesenchymal intermediate filament supporting mechano-structural integrity of quiescent cells while participating in adhesion, migration, survival, and cell signaling processes via dynamic assembly/disassembly in activated cells. Soft tissue sarcomas and some epit...

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Detalhes bibliográficos
Main Authors: Lahat, Guy, Zhu, Quan-Sheng, Huang, Kai-Lieh, Wang, Suizhao, Bolshakov, Svetlana, Liu, Jeffery, Torres, Keila, Langley, Robert R., Lazar, Alexander J., Hung, Mien Chie, Lev, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855704/
https://ncbi.nlm.nih.gov/pubmed/20419128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010105
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