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DNA Damage-induced Nuclear Export of Precursor MicroRNAs is Regulated by the ATM-AKT Pathway

Expression of miRNAs involves transcription of miRNA genes and maturation of the primary transcripts. Recent studies have shown that post-transcriptional processing of primary and precursor miRNAs are induced after DNA damage through regulatory RNA-binding proteins in the Drosha and Dicer complexes,...

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Detalhes bibliográficos
Main Authors: Wan, Guohui, Zhang, Xinna, Langley, Robert R., Liu, Yunhua, Hu, Xiaoxiao, Han, Cecil, Peng, Guang, Ellis, Lee M., Jones, Stephen N., Lu, Xiongbin
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796289/
https://ncbi.nlm.nih.gov/pubmed/23791529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.038
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