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The ATM Kinase Induces MicroRNA Biogenesis in the DNA Damage Response
The DNA damage response involves a complex network of processes that detect and repair DNA damage. Here we show that miRNA biogenesis is globally induced upon DNA damage in an ATM-dependent manner. About one fourth of miRNAs are significantly up-regulated after DNA damage, while loss of ATM abolishe...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3114434/ https://ncbi.nlm.nih.gov/pubmed/21329876 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.01.020 |
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