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The RNA-Binding Protein DDX1 Promotes Primary MicroRNA Maturation and Inhibits Ovarian Tumor Progression

Posttranscriptional maturation is a critical step in microRNA (miRNA) biogenesis that determines mature miRNA levels. In addition to core components (Drosha and DGCR8 [DiGeorge syndrome critical region gene 8]) in the microprocessor, regulatory RNA-binding proteins may confer the specificity for rec...

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Detalhes bibliográficos
Main Authors: Cecil Han, Yunhua Liu, Guohui Wan, Hyun Jin Choi, Luqing Zhao, Cristina Ivan, Xiaoming He, Anil K. Sood, Xinna Zhang, Xiongbin Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014-09-01
Colecção:Cell Reports
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2211124714006603
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