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The ATM Kinase Induces MicroRNA Biogenesis in the DNA Damage Response

The DNA damage response involves a complex network of processes that detect and repair DNA damage. Here we show that miRNA biogenesis is globally induced upon DNA damage in an ATM-dependent manner. About one fourth of miRNAs are significantly up-regulated after DNA damage, while loss of ATM abolishe...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Xinna, Wan, Guohui, Berger, Franklin G., He, Xiaoming, Lu, Xiongbin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114434/
https://ncbi.nlm.nih.gov/pubmed/21329876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.01.020
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