Role of the endothelin axis in astrocyte- and endothelial cell-mediated chemoprotection of cancer cells

BACKGROUND: Recent evidence suggests that astrocytes protect cancer cells from chemotherapy by stimulating upregulation of anti-apoptotic genes in those cells. We investigated the possibility that activation of the endothelin axis orchestrates survival gene expression and chemoprotection in MDA-MB-2...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Kim, Seung Wook, Choi, Hyun Jin, Lee, Ho-Jeong, He, Junqin, Wu, Qiuyu, Langley, Robert R., Fidler, Isaiah J., Kim, Sun-Jin
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232084/
https://ncbi.nlm.nih.gov/pubmed/25008093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou128
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