Amiodarone sensitizes human glioma cells but not astrocytes to TRAIL-induced apoptosis via CHOP-mediated DR5 upregulation

Amiodarone is a widely used anti-arrhythmic drug that inhibits diverse ion channels, including the Na(+)/Ca(2+) exchanger (NCX), L-type Ca(2+) channels, and Na(+) channels. Here, we report that subtoxic doses of amiodarone and tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) synergist...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, In Young, Kang, You Jung, Yoon, Mi Jin, Kim, Eun Hee, Kim, Seung U, Kwon, Taeg Kyu, Kim, In Ah, Choi, Kyeong Sook
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2011
Aiheet:
Basic and Translational Investigations
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064603/
https://ncbi.nlm.nih.gov/pubmed/21292685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq195
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia