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Lestaurtinib potentiates TRAIL‐induced apoptosis in glioma via CHOP‐dependent DR5 induction

Lestaurtinib, also called CEP‐701, is an inhibitor of tyrosine kinase, causes haematological remission in patients with AML possessing FLT3‐ITD (FLT3 gene) internal tandem duplication and strongly inhibits tyrosine kinase FLT3. Treatment with lestaurtinib modulates various signalling pathways and le...

詳細記述

保存先:
書誌詳細
出版年:J Cell Mol Med
主要な著者: Cao, Yingxiao, Kong, Shiqi, Xin, Yuling, Meng, Yan, Shang, Shuling, Qi, Yanhui
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348155/
https://ncbi.nlm.nih.gov/pubmed/32441887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15415
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