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Lestaurtinib potentiates TRAIL‐induced apoptosis in glioma via CHOP‐dependent DR5 induction

Lestaurtinib, also called CEP‐701, is an inhibitor of tyrosine kinase, causes haematological remission in patients with AML possessing FLT3‐ITD (FLT3 gene) internal tandem duplication and strongly inhibits tyrosine kinase FLT3. Treatment with lestaurtinib modulates various signalling pathways and le...

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Bibliografiske detaljer
Udgivet i:J Cell Mol Med
Main Authors: Cao, Yingxiao, Kong, Shiqi, Xin, Yuling, Meng, Yan, Shang, Shuling, Qi, Yanhui
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348155/
https://ncbi.nlm.nih.gov/pubmed/32441887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15415
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