Lestaurtinib potentiates TRAIL‐induced apoptosis in glioma via CHOP‐dependent DR5 induction

Lestaurtinib, also called CEP‐701, is an inhibitor of tyrosine kinase, causes haematological remission in patients with AML possessing FLT3‐ITD (FLT3 gene) internal tandem duplication and strongly inhibits tyrosine kinase FLT3. Treatment with lestaurtinib modulates various signalling pathways and le...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Cao, Yingxiao, Kong, Shiqi, Xin, Yuling, Meng, Yan, Shang, Shuling, Qi, Yanhui
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348155/
https://ncbi.nlm.nih.gov/pubmed/32441887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15415
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