Generation of an Immortalized Astrocyte Cell Line from H-2K(b)-tsA58 Mice to Study the Role of Astrocytes in Brain Metastasis

Astrocytes play a critical role in maintaining cerebral homeostasis and their dysregulation is thought to contribute to the pathogenesis of several diseases, including brain cancer and metastasis. Similar to the human disease, we found that lung and melanoma metastases in the mouse brain are accompa...

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Bibliographic Details
Main Authors: Langley, Robert R., Fan, Dominic, Guo, Lixia, Zhang, Chenyu, Lin, Qingtang, Brantley, Emily C., McCarty, Joseph H., Fidler, Isaiah J.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2882684/
https://ncbi.nlm.nih.gov/pubmed/19724901
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