Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2K(b)tsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy

X-linked adrenoleukodystrophy (X-ALD) is an inherited metabolic disease characterized by inflammatory demyelination, and activated astrocytes as well as microglia are thought to be involved in its pathogenesis. Conditionally immortalized astrocytic cell clones were prepared from wild-type or Abcd1-d...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Morita, Masashi, Toida, Ai, Horiuchi, Yuki, Watanabe, Shiro, Sasahara, Masakiyo, Kawaguchi, Kosuke, So, Takanori, Imanaka, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7892932/
https://ncbi.nlm.nih.gov/pubmed/33659749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2021.e06228
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