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Acyl-CoA thioesterase activity of peroxisomal ABC protein ABCD1 is required for the transport of very long-chain acyl-CoA into peroxisomes

The ABCD1 protein, one of the four ATP-binding cassette (ABC) proteins in subfamily D, is located on the peroxisomal membrane and is involved in the transport of very long chain fatty acid (VLCFA)-CoA into peroxisomes. Its mutation causes X-linked adrenoleukodystophy (X-ALD): an inborn error of pero...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kawaguchi, Kosuke, Mukai, Emi, Watanabe, Shiro, Yamashita, Atsushi, Morita, Masashi, So, Takanori, Imanaka, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7838297/
https://ncbi.nlm.nih.gov/pubmed/33500543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81949-3
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