The lysosomal protein ABCD4 can transport vitamin B(12) across liposomal membranes in vitro

Vitamin B(12) (cobalamin) is an essential micronutrient for human health, and mutation and dysregulation of cobalamin metabolism are associated with serious diseases, such as methylmalonic aciduria and homocystinuria. Mutations in ABCD4 or LMBRD1, which encode the ABC transporter ABCD4 and lysosomal...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kitai, Katsuki, Kawaguchi, Kosuke, Tomohiro, Takenori, Morita, Masashi, So, Takanori, Imanaka, Tsuneo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113721/
https://ncbi.nlm.nih.gov/pubmed/33845046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100654
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