A Homeobox Gene Related to Drosophila Distal-Less Promotes Ovarian Tumorigenicity by Inducing Expression of Vascular Endothelial Growth Factor and Fibroblast Growth Factor-2

Homeobox genes control developmental patterning and are increasingly being found to be deregulated in tumors. The DLX4 homeobox gene maps to the 17q21.3-q22 region that is amplified in some epithelial ovarian cancers. Because amplification of this region correlates with poor prognosis, we investigat...

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Detalhes bibliográficos
Main Authors: Hara, Fumikata, Samuel, Shaija, Liu, Jinsong, Rosen, Daniel, Langley, Robert R., Naora, Honami
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1854954/
https://ncbi.nlm.nih.gov/pubmed/17456765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.061025
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