ACAT INHIBITION AND AMYLOID BETA REDUCTION

بواسطة Bhattacharyya, Raja, Kovacs, Dora M.
منشور في 2010

The Many Substrates of Presenilin/γ-Secretase

بواسطة Haapasalo, Annakaisa, Kovacs, Dora M.
منشور في 2011

ACAT as a Drug Target for Alzheimer's Disease

بواسطة Huttunen, Henri J., Kovacs, Dora M.
منشور في 2008

Surface Trafficking of Sodium Channels in Cells and in Hippocampal Slices

بواسطة Kim, Doo Yeon, Kovacs, Dora M.
منشور في 2011

Palmitoylation of Amyloid Precursor Protein Regulates Amyloidogenic Processing in Lipid Rafts

بواسطة Bhattacharyya, Raja, Barren, Cory, Kovacs, Dora M.
منشور في 2013

Knockdown of ACAT-1 Reduces Amyloidogenic Processing of APP

بواسطة Huttunen, Henri J., Greco, Christopher, Kovacs, Dora M.
منشور في 2007

Alzheimer’s secretases regulate voltage-gated sodium channels

بواسطة Kovacs, Dora M., Gersbacher, Manuel T., Kim, Doo Yeon
منشور في 2010

Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins

بواسطة Carey, Bryce W., Kim, Doo Y., Kovacs, Dora M.
منشور في 2006

The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

بواسطة Vassar, Robert, Kovacs, Dora M., Yan, Riqiang, Wong, Philip C.
منشور في 2009

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

بواسطة Gersbacher, Manuel T, Kim, Doo Yeon, Bhattacharyya, Raja, Kovacs, Dora M
منشور في 2010

Reduced Sodium Channel Na(v)1.1 Levels in BACE1-null Mice

بواسطة Kim, Doo Yeon, Gersbacher, Manuel T., Inquimbert, Perrine, Kovacs, Dora M.
منشور في 2011

BACE1 activity regulates cell surface contactin-2 levels

بواسطة Gautam, Vivek, D’Avanzo, Carla, Hebisch, Matthias, Kovacs, Dora M, Kim, Doo Yeon
منشور في 2014

Synaptotagmins interact with APP and promote Aβ generation

بواسطة Gautam, Vivek, D’Avanzo, Carla, Berezovska, Oksana, Tanzi, Rudolph E., Kovacs, Dora M.
الحاوية / القاعدة Mol Neurodegener (2015)

Palmitoylated APP Forms Dimers, Cleaved by BACE1

بواسطة Bhattacharyya, Raja, Fenn, Rebecca H., Barren, Cory, Tanzi, Rudolph E., Kovacs, Dora M.
الحاوية / القاعدة PLoS One (2016)

Novel N-terminal Cleavage of APP Precludes Aβ Generation in ACAT-Defective AC29 Cells

بواسطة Huttunen, Henri J., Puglielli, Luigi, Ellis, Blake C., Ingano, Laura A. MacKenzie, Kovacs, Dora M.
منشور في 2008

The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells

بواسطة Kim, Doo Yeon, Wertz, Mary H., Gautam, Vivek, D'Avanzo, Carla, Bhattacharyya, Raja, Kovacs, Dora M.
منشور في 2013

γ-Secretase modulators reduce endogenous amyloid β(42) levels in human neural progenitor cells without altering neuronal differentiation

بواسطة D’Avanzo, Carla, Sliwinski, Christopher, Wagner, Steven L., Tanzi, Rudolph E., Kim, Doo Yeon, Kovacs, Dora M.
الحاوية / القاعدة FASEB J (2015)

BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

بواسطة Sachse, Carolyn C., Kim, Young Hye, Agsten, Marianne, Huth, Tobias, Alzheimer, Christian, Kovacs, Dora M., Kim, Doo Yeon
منشور في 2013

Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes

بواسطة Bhattacharyya, Raja, Black, Sophia E., Lotlikar, Madhura S., Fenn, Rebecca H., Jorfi, Mehdi, Kovacs, Dora M., Tanzi, Rudolph E.
الحاوية / القاعدة Cell Rep (2021)

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

بواسطة Huttunen, Henri J., Peach, Camilla, Bhattacharyya, Raja, Barren, Cory, Pettingell, Warren, Hutter-Paier, Birgit, Windisch, Manfred, Berezovska, Oksana, Kovacs, Dora M.
منشور في 2009