Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins

HLA (human leucocyte antigen)-A2 is an MHC Class I protein with primary functions in T-cell development and initi-ation of immune cell responses. MHC I proteins also play roles in intercellular adhesion, apoptosis, cell proliferation and neuronal plasticity. By utilizing a sequence comparison analys...

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Autori principali: Carey, Bryce W., Kim, Doo Y., Kovacs, Dora M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2006
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698663/
https://ncbi.nlm.nih.gov/pubmed/17150042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060847
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