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Presenilin/γ-Secretase Cleaves CD46 in Response to Neisseria Infection

CD46 is a type I transmembrane protein with complement and T cell regulatory functions in human cells. CD46 has signaling and receptor properties in immune and nonimmune cells, many of which are dependent on the expression of cytoplasmic tail (cyt) isoforms cyt1 or cyt2. Little is known about how cy...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Weyand, Nathan J., Calton, Christine M., Higashi, Dustin L., Kanack, Kristen J., So, Magdalene
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5141583/
https://ncbi.nlm.nih.gov/pubmed/20018629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900522
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