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Neisseria gonorrhoeae evades autophagic killing by downregulating CD46-cyt1 and remodeling lysosomes

The Gram-negative human pathogen N. gonorrhoeae (Ngo) quickly attaches to epithelial cells, and large numbers of the bacteria remain on the cell surface for prolonged periods. Ngo invades cells but few viable intracellular bacteria are recovered until later stages of infection, leading to the assump...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Kim, Won J., Mai, Annette, Weyand, Nathan J., Rendón, Maria A., Van Doorslaer, Koenraad, So, Magdalene
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388937/
https://ncbi.nlm.nih.gov/pubmed/30753248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007495
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