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BACE1 activity regulates cell surface contactin-2 levels
BACKGROUND: Although BACE1 is a major therapeutic target for Alzheimer’s disease (AD), potential side effects of BACE1 inhibition are not well characterized. BACE1 cleaves over 60 putative substrates, however the majority of these cleavages have not been characterized. Here we investigated BACE1-med...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3899608/ https://ncbi.nlm.nih.gov/pubmed/24405708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-4 |
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