Caricamento...
γ-Secretase modulators reduce endogenous amyloid β(42) levels in human neural progenitor cells without altering neuronal differentiation
Soluble γ-secretase modulators (SGSMs) selectively decrease toxic amyloid β (Aβ) peptides (Aβ(42)). However, their effect on the physiologic functions of γ-secretase has not been tested in human model systems. γ-Secretase regulates fate determination of neural progenitor cells. Thus, we studied the...
Salvato in:
| Pubblicato in: | FASEB J |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Federation of American Societies for Experimental Biology
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4511200/ https://ncbi.nlm.nih.gov/pubmed/25903103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-271015 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|