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Potential Use of γ-Secretase Modulators in the Treatment of Alzheimer Disease

Although significant progress has occurred in the past 20 years regarding our understanding of Alzheimer disease pathogenesis, we have yet to identify disease-modifying therapeutics capable of substantially altering the clinical course of this prevalent neurodegenerative disease. In this short revie...

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Detalhes bibliográficos
Main Authors: Wagner, Steven L., Tanzi, Rudolph E., Mobley, William C., Galasko, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747667/
https://ncbi.nlm.nih.gov/pubmed/22801784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2012.540
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