Resultados da pesquisa por Autor

1

ACAT INHIBITION AND AMYLOID BETA REDUCTION

ACAT INHIBITION AND AMYLOID BETA REDUCTION

Por Bhattacharyya, Raja, Kovacs, Dora M.
Publicado em 2010

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2

The Many Substrates of Presenilin/γ-Secretase

The Many Substrates of Presenilin/γ-Secretase

Por Haapasalo, Annakaisa, Kovacs, Dora M.
Publicado em 2011

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3

ACAT as a Drug Target for Alzheimer's Disease

ACAT as a Drug Target for Alzheimer's Disease

Por Huttunen, Henri J., Kovacs, Dora M.
Publicado em 2008

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4

Surface Trafficking of Sodium Channels in Cells and in Hippocampal Slices

Surface Trafficking of Sodium Channels in Cells and in Hippocampal Slices

Por Kim, Doo Yeon, Kovacs, Dora M.
Publicado em 2011

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5

Palmitoylation of Amyloid Precursor Protein Regulates Amyloidogenic Processing in Lipid Rafts

Palmitoylation of Amyloid Precursor Protein Regulates Amyloidogenic Processing in Lipid Rafts

Por Bhattacharyya, Raja, Barren, Cory, Kovacs, Dora M.
Publicado em 2013

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6

Knockdown of ACAT-1 Reduces Amyloidogenic Processing of APP

Knockdown of ACAT-1 Reduces Amyloidogenic Processing of APP

Por Huttunen, Henri J., Greco, Christopher, Kovacs, Dora M.
Publicado em 2007

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7

Alzheimer’s secretases regulate voltage-gated sodium channels

Alzheimer’s secretases regulate voltage-gated sodium channels

Por Kovacs, Dora M., Gersbacher, Manuel T., Kim, Doo Yeon
Publicado em 2010

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8

Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins

Presenilin/γ-secretase and α-secretase-like peptidases cleave human MHC Class I proteins

Por Carey, Bryce W., Kim, Doo Y., Kovacs, Dora M.
Publicado em 2006

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9

The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

The β-Secretase Enzyme BACE in Health and Alzheimer's Disease: Regulation, Cell Biology, Function, and Therapeutic Potential

Por Vassar, Robert, Kovacs, Dora M., Yan, Riqiang, Wong, Philip C.
Publicado em 2009

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10

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

Por Gersbacher, Manuel T, Kim, Doo Yeon, Bhattacharyya, Raja, Kovacs, Dora M
Publicado em 2010

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11

Reduced Sodium Channel Na(v)1.1 Levels in BACE1-null Mice

Reduced Sodium Channel Na(v)1.1 Levels in BACE1-null Mice

Por Kim, Doo Yeon, Gersbacher, Manuel T., Inquimbert, Perrine, Kovacs, Dora M.
Publicado em 2011

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12

BACE1 activity regulates cell surface contactin-2 levels

BACE1 activity regulates cell surface contactin-2 levels

Por Gautam, Vivek, D’Avanzo, Carla, Hebisch, Matthias, Kovacs, Dora M, Kim, Doo Yeon
Publicado em 2014

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13

Synaptotagmins interact with APP and promote Aβ generation

Synaptotagmins interact with APP and promote Aβ generation

Por Gautam, Vivek, D’Avanzo, Carla, Berezovska, Oksana, Tanzi, Rudolph E., Kovacs, Dora M.
Publicado no Mol Neurodegener (2015)

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14

Palmitoylated APP Forms Dimers, Cleaved by BACE1

Palmitoylated APP Forms Dimers, Cleaved by BACE1

Por Bhattacharyya, Raja, Fenn, Rebecca H., Barren, Cory, Tanzi, Rudolph E., Kovacs, Dora M.
Publicado no PLoS One (2016)

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15

Novel N-terminal Cleavage of APP Precludes Aβ Generation in ACAT-Defective AC29 Cells

Novel N-terminal Cleavage of APP Precludes Aβ Generation in ACAT-Defective AC29 Cells

Por Huttunen, Henri J., Puglielli, Luigi, Ellis, Blake C., Ingano, Laura A. MacKenzie, Kovacs, Dora M.
Publicado em 2008

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16

The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells

The E280A presenilin mutation reduces voltage-gated sodium channel levels in neuronal cells

Por Kim, Doo Yeon, Wertz, Mary H., Gautam, Vivek, D'Avanzo, Carla, Bhattacharyya, Raja, Kovacs, Dora M.
Publicado em 2013

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17

γ-Secretase modulators reduce endogenous amyloid β(42) levels in human neural progenitor cells without altering neuronal differentiation

γ-Secretase modulators reduce endogenous amyloid β(42) levels in human neural progenitor cells without altering neuronal differentiation

Por D’Avanzo, Carla, Sliwinski, Christopher, Wagner, Steven L., Tanzi, Rudolph E., Kim, Doo Yeon, Kovacs, Dora M.
Publicado no FASEB J (2015)

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18

BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

BACE1 and presenilin/γ-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels

Por Sachse, Carolyn C., Kim, Young Hye, Agsten, Marianne, Huth, Tobias, Alzheimer, Christian, Kovacs, Dora M., Kim, Doo Yeon
Publicado em 2013

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19

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

Inhibition of acyl-coenzyme A: cholesterol acyl transferase modulates amyloid precursor protein trafficking in the early secretory pathway

Por Huttunen, Henri J., Peach, Camilla, Bhattacharyya, Raja, Barren, Cory, Pettingell, Warren, Hutter-Paier, Birgit, Windisch, Manfred, Berezovska, Oksana, Kovacs, Dora M.
Publicado em 2009

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20

The Acyl-Coenzyme A:Cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid Pathology in Aged Amyloid Precursor Protein Transgenic Mice

The Acyl-Coenzyme A:Cholesterol Acyltransferase Inhibitor CI-1011 Reverses Diffuse Brain Amyloid Pathology in Aged Amyloid Precursor Protein Transgenic Mice

Por Huttunen, Henri J., Havas, Daniel, Peach, Camilla, Barren, Cory, Duller, Stephan, Xia, Weiming, Frosch, Matthew P., Hutter-Paier, Birgit, Windisch, Manfred, Kovacs, Dora M.
Publicado em 2010

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