A Mentoring Program to Help Junior Faculty Members Achieve Scholarship Success

Por Kohn, Harold
Publicado em 2014

Triphenylphosphine Dibromide: A Simple One–pot Esterification Reagent

Por Salomé, Christophe, Kohn, Harold
Publicado em 2009

Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives

Por Morieux, Pierre, Stables, James P., Kohn, Harold
Publicado em 2008

A Novel Automated Lazy Learning QSAR (ALL-QSAR) Approach: Method Development, Applications, and Virtual Screening of Chemical Databases Using Validated ALL-QSAR Models

Por Zhang, Shuxing, Golbraikh, Alexander, Oloff, Scott, Kohn, Harold, Tropsha, Alexander
Publicado em 2006

Merging the Structural Motifs of Functionalized Amino Acids and α-Aminoamides: Compounds with Significant Anticonvulsant Activities

Por Salomé, Christophe, Salomé-Grosjean, Elise, Stables, James P., Kohn, Harold
Publicado em 2010

The Structure-Activity Relationship of the 3-Oxy Site in the Anticonvulsant (R)-N-Benzyl 2-Acetamido-3-methoxypropionamide

Por Morieux, Pierre, Salomé, Christophe, Park, Ki Duk, Stables, James P., Kohn, Harold
Publicado em 2010

Defining the Structural Parameters that Confer Anticonvulsant Activity by the Site-by-Site Modification of (R)-N′-Benzyl 2- Amino-3-methylbutanamide

Por King, Amber, De Ryck, Marc, Kaminski, Rafal, Valade, Anne, Stables, James P., Kohn, Harold
Publicado em 2011

Chimeric Derivatives of Functionalized Amino Acids and α-Aminoamides: Compounds with Anticonvulsant Activity in Seizure Models and Inhibitory Actions on Central, Peripheral, and Ca...

Por Torregrosa, Robert, Yang, Xiao-Fang, Dustrude, Erik T., Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Publicado no Bioorg Med Chem (2015)

Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties

Por Park, Ki Duk, Yang, Xiao-Fang, Lee, Hyosung, Dustrude, Erik T., Wang, Yuying, Khanna, Rajesh, Kohn, Harold
Publicado em 2012

Identification of a Lacosamide Binding Protein Using an Affinity Bait and Chemical Reporter Strategy: 14-3-3 ζ

Por Park, Ki Duk, Kim, Dong Wook, Reamtong, Onrapak, Eyers, Claire, Gaskell, Simon J., Liu, Rihe, Kohn, Harold
Publicado em 2011

(Biphenyl-4-yl)methylammonium Chlorides: Potent Anticonvulsants That Modulate Na(+) Currents

Por Lee, Hyosung, Park, Ki Duk, Yang, Xiao-Fang, Dustrude, Erik T., Wilson, Sarah M., Khanna, Rajesh, Kohn, Harold
Publicado em 2013

Development and Characterization of Novel Derivatives of the Antiepileptic Drug Lacosamide That Exhibit Far Greater Enhancement in Slow Inactivation of Voltage-Gated Sodium Channel...

Por Wang, Yuying, Park, Ki Duk, Salomé, Christophe, Wilson, Sarah M., Stables, James P., Liu, Rihe, Khanna, Rajesh, Kohn, Harold
Publicado em 2010

Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, a...

Por Park, Ki Duk, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Ripsch, Matthew S., White, Fletcher A., Khanna, Rajesh, Kohn, Harold
Publicado no ACS Chem Neurosci (2014)

Synthesis and Anticonvulsant Activities of (R)-N-(4′-Substituted) benzyl 2-Acetamido-3-methoxypropionamides

Por Salomé, Christophe, Salomé-Grosjean, Elise, Park, Ki Duk, Morieux, Pierre, Swendiman, Robert, DeMarco, Erica, Stables, James P., Kohn, Harold
Publicado em 2010

Merging Structural Motifs of Functionalized Amino Acids and α-Aminoamides Results in Novel Anticonvulsant Compounds with Significant Effects on Slow and Fast Inactivation of Voltag...

Por Wang, Yuying, Wilson, Sarah M., Brittain, Joel M., Ripsch, Matthew S., Salomé, Christophe, Park, Ki Duk, White, Fletcher A., Khanna, Rajesh, Kohn, Harold
Publicado em 2011

Lacosamide Isothiocyanate-based Agents: Novel Agents to Target and Identify Lacosamide Receptors

Por Park, Ki Duk, Morieux, Pierre, Salomé, Christophe, Cotten, Steven W., Reamtong, Onrapak, Eyers, Claire, Gaskell, Simon J., Stables, James P., Liu, Rihe, Kohn, Harold
Publicado em 2009

Substituted N-(Biphenyl-4′-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels...

Por Lee, Hyosung, Park, Ki Duk, Torregrosa, Robert, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Wilson, Sarah M., Barbosa, Cindy, Xiao, Yucheng, Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Publicado em 2014

Identification of the Benzyloxyphenyl Pharmacophore: A Structural Unit That Promotes Sodium Channel Slow Inactivation

Por King, Amber M., Yang, Xiao-Fang, Wang, Yuying, Dustrude, Erik T., Barbosa, Cindy, Due, Michael R., Piekarz, Andrew D., Wilson, Sarah M., White, Fletcher A., Salomé, Christophe, Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Publicado em 2012

Translational Stroke Research: Vision and Opportunities

Por Bosetti, Francesca, Koenig, James I, Ayata, Cenk, Back, Stephen A, Becker, Kyra, Broderick, Joseph P, Carmichael, S Thomas, Cho, Sunghee, Cipolla, Marilyn, Corbett, Dale, Corriveau, Roderick, Cramer, Steven C, Ferguson, Adam R, Finklestein, Seth, Ford, Byron D, Furie, Karen, Hemmen, Thomas M, Iadecola, Costantino, Jakeman, Lyn, Janis, Scott, Jauch, Edward C, Johnston, Karen, Kochanek, Patrick M, Kohn, Harold, Lo, Eng H, Lyden, Patrick D, Mallard, Carina, McCullough, Louise D, McGavern, Linda, Meschia, James F, Moy, Claudia, Perez-Pinzon, Miguel, Ramadan, Ipolia, Savitz, Sean I, Schwamm, Lee H, Steinberg, Gary K, Stenzel-Poore, Mary, Tymianski, Michael, Warach, Steven, Wechsler, Lawrence R, Zhang, John H, Koroshetz, Walter
Publicado no Stroke (2017)