Mining the Na(V)1.7 interactome: Opportunities for chronic pain therapeutics

od Chew, Lindsey A., Bellampalli, Shreya S., Dustrude, Erik T., Khanna, Rajesh
Wydane w Biochem Pharmacol (2019)

CRMP2 Protein SUMOylation Modulates NaV1.7 Channel Trafficking

od Dustrude, Erik T., Wilson, Sarah M., Ju, Weina, Xiao, Yucheng, Khanna, Rajesh
Wydane 2013

Hierarchical CRMP2 posttranslational modifications control NaV1.7 function

od Dustrude, Erik T., Moutal, Aubin, Yang, Xiaofang, Wang, Yuying, Khanna, May, Khanna, Rajesh
Wydane w Proc Natl Acad Sci U S A (2016)

Chimeric Derivatives of Functionalized Amino Acids and α-Aminoamides: Compounds with Anticonvulsant Activity in Seizure Models and Inhibitory Actions on Central, Peripheral, and Ca...

od Torregrosa, Robert, Yang, Xiao-Fang, Dustrude, Erik T., Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Wydane w Bioorg Med Chem (2015)

A single structurally conserved SUMOylation site in CRMP2 controls NaV1.7 function

od Dustrude, Erik Thomas, Perez-Miller, Samantha, François-Moutal, Liberty, Moutal, Aubin, Khanna, May, Khanna, Rajesh
Wydane w Channels (Austin) (2017)

Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties

od Park, Ki Duk, Yang, Xiao-Fang, Lee, Hyosung, Dustrude, Erik T., Wang, Yuying, Khanna, Rajesh, Kohn, Harold
Wydane 2012

(Biphenyl-4-yl)methylammonium Chlorides: Potent Anticonvulsants That Modulate Na(+) Currents

od Lee, Hyosung, Park, Ki Duk, Yang, Xiao-Fang, Dustrude, Erik T., Wilson, Sarah M., Khanna, Rajesh, Kohn, Harold
Wydane 2013

Chimeric Agents Derived from the Functionalized Amino Acid, Lacosamide, and the α-Aminoamide, Safinamide: Evaluation of Their Inhibitory Actions on Voltage-Gated Sodium Channels, a...

od Park, Ki Duk, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Ripsch, Matthew S., White, Fletcher A., Khanna, Rajesh, Kohn, Harold
Wydane w ACS Chem Neurosci (2014)

Carbamazepine Potentiates the Effectiveness of Morphine in a Rodent Model of Neuropathic Pain

od Due, Michael R., Yang, Xiao-Fang, Allette, Yohance M., Randolph, Aaron L., Ripsch, Matthew S., Wilson, Sarah M., Dustrude, Erik T., Khanna, Rajesh, White, Fletcher A.
Wydane 2014

Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear

od Dustrude, Erik T., Caliman, Izabela F., Bernabe, Cristian S., Fitz, Stephanie D., Grafe, Laura A., Bhatnagar, Seema, Bonaventure, Pascal, Johnson, Philip L., Molosh, Andrei I., Shekhar, Anantha
Wydane w Front Neurosci (2018)

Inhibition of the Ubc9 E2 SUMO conjugating enzyme–CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain

od François-Moutal, Liberty, Dustrude, Erik T., Wang, Yue, Brustovetsky, Tatiana, Dorame, Angie, Ju, Weina, Moutal, Aubin, Perez-Miller, Samantha, Brustovetsky, Nickolay, Gokhale, Vijay, Khanna, May, Khanna, Rajesh
Wydane w Pain (2018)

Substituted N-(Biphenyl-4′-yl)methyl (R)-2-Acetamido-3-methoxypropionamides: Potent Anticonvulsants That Affect Frequency (Use) Dependence and Slow Inactivation of Sodium Channels...

od Lee, Hyosung, Park, Ki Duk, Torregrosa, Robert, Yang, Xiao-Fang, Dustrude, Erik T., Wang, Yuying, Wilson, Sarah M., Barbosa, Cindy, Xiao, Yucheng, Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Wydane 2014

Inhibition of Transmitter Release and Attenuation of Anti-retroviral-associated and Tibial Nerve Injury-related Painful Peripheral Neuropathy by Novel Synthetic Ca(2+) Channel Pept...

od Wilson, Sarah M., Schmutzler, Brian S., Brittain, Joel M., Dustrude, Erik T., Ripsch, Matthew S., Pellman, Jessica J., Yeum, Tae-Sung, Hurley, Joyce H., Hingtgen, Cynthia M., White, Fletcher A., Khanna, Rajesh
Wydane 2012

Homology‐guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2‐derived peptides

od Moutal, Aubin, Li, Wennan, Wang, Yue, Ju, Weina, Luo, Shizhen, Cai, Song, François‐Moutal, Liberty, Perez‐Miller, Samantha, Hu, Jackie, Dustrude, Erik T, Vanderah, Todd W, Gokhale, Vijay, Khanna, May, Khanna, Rajesh
Wydane w Br J Pharmacol (2017)

Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors

od Moutal, Aubin, Wang, Yue, Yang, Xiaofang, Ji, Yingshi, Luo, Shizhen, Dorame, Angie, Bellampalli, Shreya S., Chew, Lindsey A., Cai, Song, Dustrude, Erik T., Keener, James E., Marty, Michael T., Vanderah, Todd W., Khanna, Rajesh
Wydane w Pain (2017)

Identification of the Benzyloxyphenyl Pharmacophore: A Structural Unit That Promotes Sodium Channel Slow Inactivation

od King, Amber M., Yang, Xiao-Fang, Wang, Yuying, Dustrude, Erik T., Barbosa, Cindy, Due, Michael R., Piekarz, Andrew D., Wilson, Sarah M., White, Fletcher A., Salomé, Christophe, Cummins, Theodore R., Khanna, Rajesh, Kohn, Harold
Wydane 2012

The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents

od Xu, Yu, Cantwell, Lucas, Molosh, Andrei I., Plant, Leigh D., Gazgalis, Dimitris, Fitz, Stephanie D., Dustrude, Erik T., Yang, Yuchen, Kawano, Takeharu, Garai, Sumanta, Noujaim, Sami F., Shekhar, Anantha, Logothetis, Diomedes E., Thakur, Ganesh A.
Wydane w J Biol Chem (2020)